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In a combined analysis of three trials with 1,119 participants, individuals with PAM variants responded less effectively to GLP-1 drugs and were less likely to reach target HbA1c levels, a measure of long-term blood sugar control
The combined cardiovascular stimulation from both drugs creates unacceptable risk for patients with compromised cardiac function
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If lower doses were effective, we would have studied them
Although side effects can occur, Ozempic has a good safety profile
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